Catalog RNAs

Etherna

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eGFP expresses an enhanced version of green fluorescent protein which yields bright green fluorescence with an emission peak at 509nm. eGFP was originally isolated from the jellyfish, Aequorea Victoria and is a commonly used as a direct detection reporter in mammalian cell culture.

Fluc expresses a luciferase protein, which emits bioluminescence in the presence of the substrate, luciferin. Fluc was originally isolated from the firefly, Photinus pyralis, and is commonly used in mammalian cell culture to assess gene expression and cell viability. Fluc mRNA can be used in vivo to track the biodistribution of the mRNA using In Vivo Bioluminescent imaging (BLI).

Our HA mRNA will express a hemagglutinin protein. The specific sequence is derived from the Influenza A Virus (A/PertoRico/8/1934/H1N1 (ACF41834.1).

This encodes the human erythropoietin (EPO) protein, a hormone naturally produced by the kidney that controls red blood cell production (erythropoiesis). EPO is also believed plays a role in wound healing and neural regeneration.

Ovalbumin (OVA), a member of the serpin family of proteins, is the predominant glycoprotein found in avian egg whites. It is commonly used in biochemical studies as a molecular weight marker and is an established model allergen for airway hyperresponsiveness.

This mRNA codes for a monomeric red fluorescent protein. It’s often used as a labeled tag for genes and cells of interest. The sequence was originally derived from Discosoma sea anemones. It has an excitation peak at 587 nm and an emission peak at 610 nm.

The lacZgene produces the enzyme beta-galactosidase. This lactose metabolism enzyme is part of the lactose operon and breaks down lactose into glucose and galactose. The protein derived from the nuclear localization signal (NLS) LacZ RNA has two nuclear localization signals to achieve transport to the nucleus. The nucleus of transfected cells will stain intense blue in the presence of XGal.